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Scientists discover world's most bitter substance — in a non-toxic mushroom

Ellsworth Toohey
Apr 24, 2025
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Close-up of a bitter bracket fungus (VillaK/shutterstock.com)

Scientists have discovered the world's most bitter substance, and shockingly, it's not the collected tears of Tesla shareholders. As reported in the Journal of Agricultural and Food Chemistry, it's in a mushroom called Amaropostia stiptica.

This mushroom contains a compound so bitter that one g…

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