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One psilocybin dose may reshape brain wiring a month later

Ellsworth Toohey
May 05, 2026
∙ Paid

image: Serrgey75/Shutterstock

A new paper in Nature Communications, covered by Ian Sample at the Guardian, claims a single 25mg dose may leave behind anatomical changes in the wiring itself, still visible 30 days on.

Researchers at UC San Francisco and Imperial College London recruited 28 psychedelic-naive adults and gave each of them a token 1mg primer, …

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